移植後糖尿病的診斷與藥物治療
Diagnosis and Treatment of Post-Transplantation Diabetes Mellitus

作者:王奕山(Yi-Shan Wang)；邱炳芳(Ping-Fang Chiu)；王心榆(Hsin-Yu Wang)

摘要
隨著醫療科技的日新月異，末期腎衰竭病人除透析外，可接受腎移植手術，大大改善日常生活品質。併發症除急慢性排斥的問題之外，移植後高血糖也是常見的併發症之一。高血糖導致代謝異常，增加高血脂症和高血壓的發生率，並加速腎功能傷害和增加感染機會，同時也是移植腎失去功能的重要原因之一。隨著新藥的研發，新一類的降血糖藥和傳統降血糖藥能否應用於這類的患者，需注意那些不良反應及使用限制，本文將探討移植後糖尿病的藥物選擇及需注意的重點。
As improving of medical care， patients with end-stage renal disease have several modalities as renal replacement therapy. In addition to dialysis， renal transplantations are growing greatly and obtain much better quality of daily life. However， it still carries some complications including rejection， infection and malignancy. High blood sugar after transplantation is also one of the common complications. Hyperglycemia leads to metabolic abnormalities， increase the incidence of hyperlipidemia and hypertension， and accelerate renal injury and increase the chance of infection. New classes of hypoglycemic agents can be applied to such patients， but attention should be paid to those adverse reactions and the use of limitations， this article will focus on the choice of drugs for post-transplant diabetes.

出處:腎臟與透析；30卷1期(2018/03/01)，P19-23