第二次腎臟移植的近況與發展 Long-Term Outcome on Second Kidney Transplantations
作者:張登翔(Teng-Hsiang Chang);張家築(Chia-Chu Chang);邱炳芳(Pin-Fang Chiou)
摘要 腎臟移植是末期腎臟病病患目前已知最好的腎臟替代治療,成功的腎臟移植可以帶給病患更好的存活率跟生活品質。近年因醫學的進步所以短期存活率有大幅度的提升,但長期存活率進步仍有限,根據國外研究顯示,一個屍體捐贈的腎臟可以使用8.8年,而活體捐贈可以使用12年,所以接受腎臟移植的患者將來很有可會遇到移植腎失敗,重新登入等待換腎名單。此篇文章主要就第一次腎臟移植失敗後的處置做討論,跟研究第二次腎臟移植的預後跟危險因子。 Renal transplantation is an optimal treatment for patients with end-stage renal disease (ESRD). In general, a successful primary (i.e., first) kidney transplantation (KT) provides substantially longer survival and better quality of life than dialysis with similar characteristics. Despite short-term graft survival has improved in the past decade, long-term graft survival is still limited. The average survival of a KT is 8.8 years for deceased and 12 years for living donor transplants. Therefore, we are seeing an increasing number of patients being relisted for a second KT worldwide as most KT patients will eventually face graft failure. The aim of this study was to discuss the management of the graft loss patient, and long-term outcomes of second kidney transplantations and risk factors predictive of second KT outcome.
出處:腎臟與透析;30卷1期(2018 / 03 / 01),P6 - 9
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