腎移植與BK病毒 BK Virus Nephropathy in Renal Transplant Recipients
作者:張晉鏵(Chin-Hua Chang) ; 張家築(Chia-Chu Chang) ; 邱炳芳(Ping-Fang Chiu)
摘要 BK病毒廣泛的存在自然環境中,常見於正常人體內,但是通常只有在免疫不全的病人身上才會造成嚴重的症狀。對腎臟移植患者,BK病毒會引起腎小管間質性腎炎以及輸尿管狹窄,甚至導致腎臟衰竭。然而,目前並無有效治療BK病毒感染的藥物。若能及早篩檢出感染的高風險族群並減少免疫抑制劑的劑量,便有機會在腎功能受到損傷之前控制感染。 Infection caused by BK virus is universal and persistent in healthy individuals. Reactivation can occur when the immune system is impaired. BK virus causes tubulointerstitial nephritis, ureter stenosis, and even graft failure. However, there is no effective treatment so far. Early detection BK nephropathy and reduction of immunosuppressant is the most important.
出處:與透析;30卷1期(2018/03/ 01),P15 - 18 |